Tissue Perfusion Monitoring System

The CapnoProbe SL Monitoring System is an on-demand tissue perfusion monitoring system for oral application. It measures sublingual (under the tongue) CO₂, also referred to as PslCO₂. This information is important because tissue CO₂ is a reflection of how well tissue is using oxygen that is being delivered to it by the blood. The only other established indicator of tissue perfusion currently available is a clinical laboratory-based measurement - arterial blood lactate. Unlike lactate, PslCO₂ does not have a long half-life in blood once it is elevated. Used with arterial blood lactate, PslCO₂ is likely to be a useful measurement for a quick, objective confirmation of tissue perfusion.

The system consists of a handheld instrument and a disposable sensor probe. The handheld instrument is small, portable, rugged and battery operated. The disposable probe contains a self-calibrating CO₂ sensor and attaches to the handheld instrument. The disposable probe is positioned under the patient's tongue like a thermometer and non-invasively measures the tissue CO₂ of the mucous membrane in the mouth in less than one minute. This non-invasive measurement may be a supporting and sensitive measure of the adequacy of blood flow at the tissue level. When sublingual CO₂ measurements are used with another sign and indication of tissue perfusion, arterial blood lactate, hypoperfusion may also be identified.

This product is in the 510(k) pre-market review process with the FDA and is not yet available for sale.

Optical Sensors Inc., 7615 Golden Triangle Drive, Ste. C, Eden Prairie, MN 55344. Tel: 952-944-5857; Fax: 952-944-6022.